Janet Dawson Selected Research

LFA 878

11/2004

Improved lymphocyte function-associated antigen-1 (LFA-1) inhibition by statin derivatives: molecular basis determined by x-ray analysis and monitoring of LFA-1 conformational changes in vitro and ex vivo.

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Janet Dawson Research Topics

Disease

10	Arthritis (Polyarthritis) 01/2022 - 01/2002
8	Inflammation (Inflammations) 01/2022 - 02/2003
7	Autoimmune Diseases (Autoimmune Disease) 01/2020 - 02/2003
3	Rheumatoid Arthritis 01/2022 - 01/2016
3	Edema (Dropsy) 02/2021 - 11/2004
2	Fibrosis (Cirrhosis) 01/2022 - 01/2016
2	Gout 01/2022 - 01/2022
2	Hypersensitivity (Allergy) 01/2017 - 10/2013
2	Neoplasms (Cancer) 12/2014 - 01/2010
2	Hyperalgesia 02/2005 - 01/2004
1	Joint Diseases (Joint Disease) 01/2022
1	Otitis 02/2021
1	Blister (Bulla) 02/2021
1	Hidradenitis Suppurativa 01/2021
1	Ulcerative Colitis 01/2021
1	Acne Vulgaris 01/2021
1	Chronic Urticaria 01/2020
1	Psoriasis (Pustulosis Palmaris et Plantaris) 09/2017
1	Acidosis 01/2017
1	T-Cell Lymphoma (Lymphoma, T Cell) 01/2017
1	Hemorrhage 01/2016
1	Necrosis 01/2016
1	Immune System Diseases (Immune Disorders) 01/2015
1	Neoplasm Metastasis (Metastasis) 12/2014
1	Lung Neoplasms (Lung Cancer) 12/2014
1	Anaphylaxis (Anaphylactic Shock) 10/2013
1	Neutropenia 03/2008
1	Ulcer 02/2005
1	Bone Neoplasms (Bone Cancer) 01/2004
1	Pain (Aches) 01/2004
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 09/2002

Drug/Important Bio-Agent (IBA)

5	AntigensIBA 10/2020 - 06/2003
4	Phosphotransferases (Kinase)IBA 01/2022 - 06/2009
4	Pharmaceutical PreparationsIBA 02/2021 - 01/2004
3	CytokinesIBA 10/2020 - 09/2002
3	Interleukin-17 (Interleukin 17)IBA 01/2018 - 01/2017
2	Transcription Factors (Transcription Factor)IBA 01/2018 - 12/2016
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2017 - 12/2016
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2017 - 02/2003
2	lumiracoxib (prexige)IBA 02/2005 - 01/2004
1	InflammasomesIBA 01/2022
1	Chemotactic FactorsIBA 01/2022
1	LipopolysaccharidesIBA 01/2022
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	Proteoglycans (Proteoglycan)IBA 01/2022
1	Uric Acid (Urate)IBA 01/2022
1	ChemokinesIBA 01/2022
1	Cantharidin (Cantharides)IBA 02/2021
1	SolutionsIBA 02/2021
1	Dexamethasone (Maxidex)FDA LinkGeneric 02/2021
1	Leukotriene B4IBA 01/2021
1	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2020
1	remibrutinibIBA 01/2020
1	Agammaglobulinaemia Tyrosine KinaseIBA 01/2020
1	Antigen-Antibody Complex (Immune Complex)IBA 10/2019
1	AminopeptidasesIBA 10/2017
1	LigandsIBA 09/2017
1	Protons (Proton)IBA 01/2017
1	NIBR-0213IBA 01/2016
1	Succinic Acid (Succinate)IBA 01/2016
1	Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 ProteinIBA 04/2015
1	Antigen Receptors (Antigen Receptor)IBA 01/2015
1	Inositol (Myoinositol)IBA 01/2015
1	Phosphatidylinositols (Phosphatidylinositol)IBA 10/2013
1	Biomarkers (Surrogate Marker)IBA 01/2010
1	Immunoglobulin G (IgG)IBA 06/2009
1	Interleukin-1 Receptor-Associated KinasesIBA 06/2009
1	ceramide kinaseIBA 03/2008
1	Diclofenac (SR 38)FDA LinkGeneric 02/2005
1	CarrageenanIBA 11/2004
1	Lymphocyte Function-Associated Antigen-1 (LFA-1)IBA 11/2004
1	Lovastatin (Mevacor)FDA LinkGeneric 11/2004
1	LFA 878IBA 11/2004
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 01/2004
1	valdecoxib (Bextra)FDA Link 01/2004
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2004
1	ferric oxide (iron oxide)IBA 06/2003
1	methylated bovine serum albumin (MBSA)IBA 06/2003
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 02/2003
1	CCR2 ReceptorsIBA 02/2003
1	Glucose (Dextrose)FDA LinkGeneric 09/2002
1	InterleukinsIBA 09/2002
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2002

Therapy/Procedure

3	Therapeutics 02/2021 - 01/2017
1	Injections 01/2022
1	Intra-Articular Injections 01/2022
1	Lasers (Laser) 12/2014
1	Catheters 12/2014
1	Tracheostomy 12/2014
1	Argon Plasma Coagulation 12/2014
1	Cautery 12/2014
1	Immunomodulation 06/2003
1	Islets of Langerhans Transplantation 09/2002